{"id":1352,"date":"2022-09-26T09:47:02","date_gmt":"2022-09-26T09:47:02","guid":{"rendered":"https:\/\/avaeh.org\/web_nueva_2021\/?p=1352"},"modified":"2022-09-26T09:47:03","modified_gmt":"2022-09-26T09:47:03","slug":"wave-life-sciences-anuncia-una-actualizacion-positiva-del-ensayo-de-fase-1b-2a-select-hd-con-resultados-iniciales-que-indican-la-participacion-de-objetivos-selectivos-de-alelos-con-wve-003-en-la-enfer","status":"publish","type":"post","link":"https:\/\/avaeh.org\/web_nueva_2021\/2022\/09\/26\/wave-life-sciences-anuncia-una-actualizacion-positiva-del-ensayo-de-fase-1b-2a-select-hd-con-resultados-iniciales-que-indican-la-participacion-de-objetivos-selectivos-de-alelos-con-wve-003-en-la-enfer\/","title":{"rendered":"Wave Life Sciences anuncia una actualizaci\u00f3n positiva del ensayo de fase 1b\/2a SELECT-HD con resultados iniciales que indican la participaci\u00f3n de objetivos selectivos de alelos con WVE-003 en la enfermedad de Huntington"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">\u00bb <em>Las dosis \u00fanicas de WVE-003 parecen generalmente seguras y bien toleradas<\/em><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><em>La prote\u00edna huntingtina mutante (mHTT) del LCR se redujo despu\u00e9s de dosis \u00fanicas de 30 o 60 mg;\u00a0la reducci\u00f3n media de mHTT en ambas cohortes fue del 22 % (reducci\u00f3n mediana del 30 %) desde el inicio 85 d\u00edas despu\u00e9s de la dosis \u00fanica<\/em>. \u00ab<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/ir.wavelifesciences.com\/news-releases\/news-release-details\/wave-life-sciences-announces-positive-update-phase-1b2a-select\" target=\"_blank\" rel=\"noreferrer noopener\">LINK A LA PUBLICACI\u00d3N EN LA WEB OFICIAL DE WAVE<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u00bb Las dosis \u00fanicas de WVE-003 parecen generalmente seguras y bien toleradas La prote\u00edna huntingtina mutante (mHTT) del LCR se redujo despu\u00e9s de dosis \u00fanicas de 30 o 60 mg;\u00a0la reducci\u00f3n media de mHTT en ambas cohortes fue del 22 % (reducci\u00f3n mediana del 30 %) desde el inicio 85 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-1352","post","type-post","status-publish","format-standard","hentry","category-sin-categoria"],"_links":{"self":[{"href":"https:\/\/avaeh.org\/web_nueva_2021\/wp-json\/wp\/v2\/posts\/1352","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/avaeh.org\/web_nueva_2021\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/avaeh.org\/web_nueva_2021\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/avaeh.org\/web_nueva_2021\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/avaeh.org\/web_nueva_2021\/wp-json\/wp\/v2\/comments?post=1352"}],"version-history":[{"count":1,"href":"https:\/\/avaeh.org\/web_nueva_2021\/wp-json\/wp\/v2\/posts\/1352\/revisions"}],"predecessor-version":[{"id":1353,"href":"https:\/\/avaeh.org\/web_nueva_2021\/wp-json\/wp\/v2\/posts\/1352\/revisions\/1353"}],"wp:attachment":[{"href":"https:\/\/avaeh.org\/web_nueva_2021\/wp-json\/wp\/v2\/media?parent=1352"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/avaeh.org\/web_nueva_2021\/wp-json\/wp\/v2\/categories?post=1352"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/avaeh.org\/web_nueva_2021\/wp-json\/wp\/v2\/tags?post=1352"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}